Data Scientist Salary: San Francisco vs Seattle

Same job, two cities — but the paycheck that looks bigger isn’t always the one that goes further. We compare gross pay, take-home after tax, and cost-of-living-adjusted real salary.

THE VERDICT
Even though a Data Scientist grosses $32,000 more in San Francisco, Seattle wins on what actually matters: after tax and cost of living, its real salary is $29,784 higher in equivalent buying power ($91,924 vs $62,140).
San Francisco, CA
Real salary $62,140 equivalent
Entry (25th)$165,000
Median (50th)$228,000
Senior (75th)$289,000
Top (90th)$363,000
65% premium vs national median. Data Scientists in San Francisco earn approximately 65% higher than the US national median for this role — a $90,000 premium on annual base salary. This reflects San Francisco's position as a higher-cost labor market where employers must match local wage norms.
Cost-of-living adjusted picture. Adjusted for San Francisco's cost-of-living index (224), the median Data Scientist salary buys the equivalent of $101,786 in a US-average-cost city. That's $36,214 less purchasing power than the national median — the higher nominal salary doesn't fully offset local costs.
HIGHER REAL PAY
Seattle, WANo state tax
Real salary $91,924 equivalent
Entry (25th)$142,000
Median (50th)$196,000
Senior (75th)$249,000
Top (90th)$312,000
42% premium vs national median. Data Scientists in Seattle earn approximately 42% higher than the US national median for this role — a $58,000 premium on annual base salary. This reflects Seattle's position as a higher-cost labor market where employers must match local wage norms.
Cost-of-living adjusted picture. Adjusted for Seattle's cost-of-living index (150), the median Data Scientist salary buys the equivalent of $130,667 in a US-average-cost city. That's $7,333 less purchasing power than the national median — the higher nominal salary doesn't fully offset local costs.

Head-to-head breakdown

MetricSan FranciscoSeattle
Median gross salary$228,000$196,000
State income tax9.3%None
Est. take-home pay$139,194$137,886
Cost-of-living index224150
Real salary (COL-adjusted take-home)$62,140$91,924

Real salary = take-home pay (after federal tax, state tax, and FICA) adjusted for each city’s cost-of-living index, shown in US-average-cost dollars. Take-home uses a 22% federal + 7.65% FICA estimate plus state tax; your actual rate depends on filing status and deductions. Methodology · Updated Q3 2026.

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