Provide and coordinate patient care, educate patients, and provide emotional support. Median salary in Cheyenne: $75K/year. Data from BLS, O*NET, and H-1B disclosures.
Figures represent annual base salary in Cheyenne, Wyoming. Reviewed by SalaryOptics Editorial · How we calculate this →
Analysis derived from the salary, COL, tax, and labor-market figures above — specific to this role and city.
Registered Nurses in Cheyenne earn approximately 9% lower than the US national median for this role — a $7,000 discount on annual base salary. Cheyenne's lower wage level partially reflects the area's cost-of-living index of 92 (US avg = 100).
Wyoming has no state income tax, which is worth roughly $6,975 per year at this salary level compared to a California Registered Nurse on the same gross pay. A Cheyenne Registered Nurse would need to earn $82,690 in California to net the same take-home.
Only 8% of Registered Nurse positions offer remote flexibility, meaning the Cheyenne salary above represents what local employers actually pay — not a remote-anywhere rate. Geographic constraints reinforce the local market, so the salary range above is more directly applicable than for remote-friendly roles.
Based on BLS 2022–2032 Employment Projections and WEF Future of Jobs Report 2026. At current growth rates, median salary reaches $88K by 2030.
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The median Registered Nurse salary in Cheyenne, WY is $75,000 per year as of Q1 2026. This figure represents the midpoint of all reported compensation for this role in the Cheyenne–WY metropolitan area, based on data from the Bureau of Labor Statistics Occupational Employment Statistics, H-1B visa disclosures from the Department of Labor, and O*NET occupational data.
Entry-level Registered Nurses in Cheyenne with 0–2 years of experience typically earn between $60,000 and $75,000 annually. Mid-career professionals with 3–7 years command $75,000 to $96,000, while senior-level practitioners with 8+ years of experience regularly earn $96,000 to $120,000 or more.
Cheyenne has a cost of living index of 92 compared to the US national average of 100. This means your salary goes approximately 8% further in Cheyenne than the national average. Crucially, Wyoming has no state income tax — giving Cheyenne-based Registered Nurses an immediate 3–5% take-home pay advantage over workers in states like California (9.3%) or New York (6.85%).
BSN or ADN; RN licensure required. 8% of these roles offer some remote flexibility.