Provide advanced nursing care including diagnosis, treatment, and prescribing medications. Median salary in Minneapolis: $133K/year. Data from BLS, O*NET, and H-1B disclosures.
Figures represent annual base salary in Minneapolis, Minnesota. Reviewed by SalaryOptics Editorial · How we calculate this →
Analysis derived from the salary, COL, tax, and labor-market figures above — specific to this role and city.
Nurse Practitioners in Minneapolis earn approximately 10% higher than the US national median for this role — a $12,000 premium on annual base salary. This reflects Minneapolis's position as a higher-cost labor market where employers must match local wage norms.
Adjusted for Minneapolis's cost-of-living index (106), the median Nurse Practitioner salary buys the equivalent of $125,472 in a US-average-cost city. That's $4,472 more purchasing power than the national median — a meaningful real-wage advantage.
Only 15% of Nurse Practitioner positions offer remote flexibility, meaning the Minneapolis salary above represents what local employers actually pay — not a remote-anywhere rate. Geographic constraints reinforce the local market, so the salary range above is more directly applicable than for remote-friendly roles.
Based on BLS 2022–2032 Employment Projections and WEF Future of Jobs Report 2026. At current growth rates, median salary reaches $133K by 2030.
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The median Nurse Practitioner salary in Minneapolis, MN is $133,000 per year as of Q1 2026. This figure represents the midpoint of all reported compensation for this role in the Minneapolis–MN metropolitan area, based on data from the Bureau of Labor Statistics Occupational Employment Statistics, H-1B visa disclosures from the Department of Labor, and O*NET occupational data.
Entry-level Nurse Practitioners in Minneapolis with 0–2 years of experience typically earn between $110,000 and $133,000 annually. Mid-career professionals with 3–7 years command $133,000 to $160,000, while senior-level practitioners with 8+ years of experience regularly earn $160,000 to $193,000 or more.
Minneapolis has a cost of living index of 106 compared to the US national average of 100. Living costs in Minneapolis are close to the national average. Minnesota has a 6.8% state income tax rate.
Master's or DNP; APRN licensure. 15% of these roles offer some remote flexibility.