Physician Assistant Salary
in Sioux Falls, SD
Practice medicine under physician supervision — diagnosing, treating, and prescribing. Median salary in Sioux Falls: $130K/year. Data from BLS, O*NET, and H-1B disclosures.
Salary range in Sioux Falls
Source: BLS OES 2026, H-1B DOL Disclosures Q1 2026. Figures represent annual base salary in Sioux Falls, South Dakota.
Key facts for Sioux Falls
Salary forecast: Sioux Falls Physician Assistant to 2030
Based on BLS 2022–2032 Employment Projections and WEF Future of Jobs Report 2025. At current growth rates, median salary reaches $162K by 2030.
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Physician Assistant Salary in Sioux Falls, South Dakota: Complete Guide (2026)
The median Physician Assistant salary in Sioux Falls, SD is $130,000 per year as of Q1 2025. This figure represents the midpoint of all reported compensation for this role in the Sioux Falls–SD metropolitan area, based on data from the Bureau of Labor Statistics Occupational Employment Statistics, H-1B visa disclosures from the Department of Labor, and O*NET occupational data.
Salary range for Physician Assistant in Sioux Falls
Entry-level Physician Assistants in Sioux Falls with 0–2 years of experience typically earn between $108,000 and $130,000 annually. Mid-career professionals with 3–7 years command $130,000 to $155,000, while senior-level practitioners with 8+ years of experience regularly earn $155,000 to $185,000 or more.
Cost of living in Sioux Falls for Physician Assistants
Sioux Falls has a cost of living index of 88 compared to the US national average of 100. This means your salary goes approximately 12% further in Sioux Falls than the national average. Crucially, South Dakota has no state income tax — giving Sioux Falls-based Physician Assistants an immediate 3–5% take-home pay advantage over workers in states like California (9.3%) or New York (6.85%).
Education requirements for Physician Assistant
Master's in Physician Assistant Studies; PA-C certification. 5% of these roles offer some remote flexibility.